安红维，国家纳米科学中心研究员，博士生导师。2023年获国家优秀青年科学基金，2023年入选北京市科技新星。国家纳米科学中心获博士学位，中国科学院高能物理研究所从事博士后，2020年任职于国家纳米科学中心。本人主要聚焦于药物递送载体与纳米生物医药前沿研究，融合人工智能辅助设计与高通量筛选技术，精准挖掘并设计多肽、糖肽功能活性序列。重点发展体内原位组装精准调控策略，建立原位纳米药物的可控构筑新方法，实现药物的靶向富集与精准递送和生物功能调控。相关研究体系面向临床前沿需求，广泛应用于生物大分子递送、靶向蛋白降解、肿瘤免疫治疗及术中精准导航等生物医药关键领域。近年来，在Sig. Transduct. Target. Ther., Adv. Mater., Nat. Commun., Angew. Chem. Int. Ed., Sci. Adv.等国际重要学术期刊上发表SCI论文50余篇；授权9项中国发明专利，临床转化应用1项，并开展研究者发起的临床研究（IIT）2项；自主研发的全球首个泛肿瘤靶向荧光造影剂分别获得中国和美国1.1类创新药物临床批件（IND）。
地址：北京市海淀区中关村北一条11号
邮编：100190
代表论著：
1. Yang, F.-Y., Zhang, N.-Y., Yang, Y., Chen, D., Wu, L.-Y., Wang, W.-K., Wang, H.-X., Wen, Z., Cai, M.-Z., Li, H.-Z., Huang, H., An, H.-W. *, Wang, H. * & Xing, N.-Z *. In vivo self-assembled nano-PROTAC for the dual degradation of AR and HSP90 to overcome castration-resistant prostate cancer resistance. Sig. Transduct. Target. Ther. 2026, 10, 346.
2. Zhang, N. Y., Wen, Z., Cai, M. Z., Zhou, K. T., Li, H. Z., Liu, Y. X., Wu, S., Xia, Y., An, H. W.* & Wang, H.* De Novo Design of Hexamer-Linker Dual-Action Nano-PROTAC for Tumor-Specific Ferroptosis. Angew. Chem. Int. Ed. Engl., 2026, 65, e09924.
3. An, H.-W., Hou, D.-Y., Zhang, N.-Y., Hu, X.-J., Yi, L., Liang, J.-X., Liu, Y.-X., Zhang, Y.-J., Liao, Y.-S., Xu, W.* & Wang, H.* A self-assembled fluorescent contrast agent targeting XIAP for image-guided surgery of bladder cancer. Nano Today 2024, 56, 102313.
4. An, H.-W. #, Hou, D.-Y. #, Yang, J., Wang, Z.-Q., Wang, M.-D., Zheng, R., Zhang, N.-Y., Hu, X.-J., Wang, Z.-J., Wang, L., Liu, D., Hao, J.-F., Xu, W.*, Zhao, Y.* & Wang, H.* A bispecific glycopeptide spatiotemporally regulates tumor microenvironment for inhibiting bladder cancer recurrence. Sci. Adv. 2023, 9, eabq8225.
5. Zhang, N.-Y., Hou, D.-Y., Hu, X.-J., Liang, J.-X., Wang, M.-D., Song, Z.-Z., Yi, L., Wang, Z.-J., An, H.-W. *, Xu, W. * & Wang, H. * Nano Proteolysis Targeting Chimeras (PROTACs) with Anti-Hook Effect for Tumor Therapy. Angew. Chem. Int. Ed. 2023, 62, e202308049.
6. Zhao, Y.-D. #, An, H.-W. #, Mamuti, M. #, Zeng, X.-Z., Zheng, R., Yang, J., Zhou, W., Liang, Y., Qin, G., Hou, D.-Y., Liu, X., Wang, H. *, Zhao, Y. * & Fang, X. * Reprogramming Hypoxic Tumor-Associated Macrophages by Nanoglycoclusters for Boosted Cancer Immunotherapy. Adv. Mater. 2023, 35, 2211332.
7. Mamuti, M., Wang, Y., Zhao, Y.-D., Wang, J.-Q., Wang, J., Fan, Y.-L., Xiao, W.-Y., Hou, D.-Y., Yang, J., Zheng, R., An, H.-W.* & Wang, H.* A Polyvalent Peptide CD40 Nanoagonist for Targeted Modulation of Dendritic Cells and Amplified Cancer Immunotherapy. Adv. Mater. 2022, 34, 2109432.
8. An, H.-W. #, Mamuti, M. #, Wang, X., Yao, H., Wang, M.-D., Zhao, L.* & Li, L.-L.*, Rationally designed modular drug delivery platform based on intracellular peptide self-assembly. Exploration 2021, 1, 20210153.
9. Zheng, Rui; Yang, Jia; Mamuti, Muhetaerjiang; Hou, Dayong, Hong-Wei An,* Yuliang Zhao, and Hao Wang*. Controllable Self-assembly of Peptide-cyanine Conjugates in Vivo as Fine-tunable Theranostics. Angew. Chem. Int. Ed.. 2021, 60, 7809-7819.
10. An, H. W., Li, L.-L., Wang, Y., Wang, Z. Q., Hou D. Y., Lin, Y.-X., Qiao, S.-L., Wang, M.-D., Yang, C., Cong, Y., Ma, Y., Zhao, X.-X., Cai, Q., Chen, W.-T., Lu, C.-Q., Xu, W. h., Wang, H.* & Zhao, Y. L.* A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging. Nat. Commun. 2019, 10, 4861.